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TR 2023/261: Long-Term Container Closure Integrity Testing of Vial-Stopper-Seal Combinations Comprising Daikyo Crystal Zenith® Vials at Ultra-Low and Cryogenic Temperatures

This document investigates 24 months of CCI of Novapure® stoppers and CZ vials using Helium leak testing.
This study investigates the container closure integrity of Novapure® stoppers used with CZ vials during storage for 24 months at ambient, ultra-low (-80C) and cryogenic (-130C) temperatures.

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