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Particle Reduction Efforts in Single use Technologies: A Case Study by West Pharmaceutical Services, Inc. and Sartorius Stedim Biotech

A method used during a manufacturing supply chain for vial stoppers and syringe plungers to improve quality and decrease the particle contamination risks.
The impact of particles is of critical importance due to the focus on patient safety, but also when considering the value of the drug product. Particle detection is challenging in single use systems due to their complexity, and concerted efforts to reduce particle generation at all steps of the manufacturing process can bring large benefits.

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