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Data-driven Control Strategy for Critical Drug Container Closure Systems (CCS) Performance at Digital Age

This presentation contains CCS stack-up tolerance analysis and statistic analysis results.
The container closure system (CCS) determines container closure integrity (CCI) performance, and CCI quality is essential for drug product integrity throughout the entire sealed drug product life cycle. A typical CCS is composed of three major components: rubber stopper, vial, and aluminum seal.

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