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Have you thought about the complexities of a patient’s journey through treatment? Navigating from leukemia diagnosis to treatment can be a difficult one. Informing family members, managing loved ones’ reactions, weighing the many different treatment options and facing the reality of multiple hospital visits can be overwhelming.
No two leukemia patients’ experiences will be the same, yet we can draw parallels across their patient journeys. So, what could you expect upon receiving a leukemia diagnosis? You will likely start with multiple blood tests and scans to get the best understanding of the type and progression of your disease. You may have a Hickman line inserted to reduce the amount of injections you might receive. You may have a course of chemotherapy administered, either as an in- or outpatient. You may be given the option of immunotherapy or a stem cell treatment that may offer you the best chance of recovery. But each of these comes with inherent risks.
While Hickman lines can be convenient, they can oftentimes become infected, which could lead to a patient facing an unexpected hospital stay for IV antibiotic treatment. Similarly, a patient suffering from hemolysis as a side effect of chemotherapy treatment may need to embark on an energy-intensive trip to their hospital’s outpatient department for a much-needed IV infusion. Such a trip could be dramatically difficult for a leukemia patient, as it would not be unrealistic to spend a whole day travelling to the hospital, receiving an IV infusion, and waiting for the side effects of any medications to wear off before driving home.
Chemotherapy, immunotherapy and stem cell treatment all come with their own inherent risks. Chemotherapy treatment runs the risk of the patient suffering from “chemo fog” which can impair memory. Hair loss, propensity to easily bruise, anaemia or a sore throat are also common side effects. Immunotherapy poses risk of side effects including skin reactions, skin redness, blistering, and dryness. The risk to patients undergoing stem cell treatment include inappropriate stem cell migration, immune rejection of transplanted stem cells, haemorrhage during neurosurgery and postoperative infection. So, there are risks with all forms of treatment for leukemia.
Being by the side of the patient is at the heart of West culture. Our teams are incredibly motivated to bring to market primary packaging which can deliver drugs to help improve patients’ lives. Our SmartDose® Drug Delivery Platform was created to improve the patient experience by helping to reduce the amount of time spent on inpatient hospital stays and outpatient department visits. The SmartDose Injector can enable self-administered, subcutaneous injections up to 10mL at a location that is convenient to the patient and away from the hospital or clinic. West’s SmartDose Injector is already approved for use with an approved drug and commercially available in the US, Europe and Japan. Contact a West representative to learn more about our oncologic drug delivery solutions.
To learn more about common challenges in developing oncology drugs and proven solutions, please visit our oncology focused page or click here for support in managing those challenges.
SmartDose® is a registered trademark of West Pharma. Services IL, Ltd., a subsidiary of West Pharmaceutical Services, Inc.
Our team in Israel, along with the rest of the world, have had a very challenging time due to the COVID-19 pandemic. In Israel, charities supporting youth in need have found this time to be particularly tough. As a result, the team came up with a novel and environmentally friendly solution to help support some of the youth in their local community.
Customers frequently ask: Do we need to wash secondary closures, such as West Flip-Off<sup>®</sup> seals? Like so many questions, the answer is “it depends”. But in general, the answer is “no”.
Lyophilization (freeze drying) is the process of dehydrating a material at low temperature and reduced pressure. It is used to extend the shelf life of many biologic drug products. Absent water, degradation processes are greatly reduced. In any primary package system (i.e., vial, elastomer stopper, seal) for a lyophilized drug product, of utmost concern are leachables and volatile organic compounds that may migrate from the elastomer stopper into the lyophilized drug product, creating a risk to patient safety.
As regulations increase across the pharmaceutical industry, reliable scientific evidence is needed to support the decisions being made during the drug development process in order to achieve the safe delivery of medicines to patients.
According to Health Resources & Services Administration (HRSA), in the US about 110,000 people are waiting for organs right now and about 20 patients die each day waiting for a transplant<sup>1</sup>. Due to shortage of donors and requirements for matching, there is a huge demand for manufactured tissues and organs. Bioprinting has emerged as a very promising tool for solving this major unmet need in healthcare.
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