April 18, 2024
Performance of NovaPure® Plungers for Syringes in Autoinjector Systems
An important element of drug product lifecycle management is anticipating use of delivery systems. When moving from vial systems to pre-filled syringes and autoinjector systems, factors to consider include patient and caregiver needs, drug product requirements, system components, and performance. This article presents performance of West’s 1-3mL and 1mL Long NovaPure® plungers versus legacy plungers for pre-filled syringes in autoinjectors; both plungers are formulation 4023/50 Gray. Performance of the NovaPure® plungers was equivalent to or better than legacy plunger performance in all aspects. Coupled with the enhanced features of NovaPure® plungers, this work indicates they are suitable when best performance is needed.
Amy A. Kim, Le Ho, Tara Haarlander and T. Page McAndrew